Our priority is researching and developing medicines and procedures that will benefit patients around the world. We are committed to addressing unmet needs across a number of important areas including, Ovarian health and anti-aging, with the goal of delivering innovative products to patients.
Use of exosomes to reseed the ovaries. This mononuclear/ stem cell treatment uses the autologous injection of mesenchymal stem cells derived from the patient’s own body to the ovaries to promote the differentiation of Germline Stem Cells into healthy follicles. The autologous nature minimizes any chances of infections and restores ovarian function. The mesenchymal stem cells have been proven to restore fertility through the reduction of apoptosis in stromal and oocytes, promote folliculogenesis and improving ovarian microenvironment.
Skin cells to human eggs. Two independent teams coaxed ordinary skin cells into a living cluster that resembled a fertilized human egg and the very first stages of a developing human embryo. Within just 10 days inside a Jello-like incubator (hydrogel) , the reverse-engineered cells showed traits astonishingly similar to their natural counterparts.
Using senolytics to eliminate senescent cells could cause a “blank slate” cenario in the ovaries. A senolytic is among a class of small molecules under current research to determine if they can selectively induce death of senescent cells and improve health in humans. Direct injection of a senolytic into the ovaries could clear such a senescent cells and Austin Biotec is moving into animal studies based on this premise.
3D printing human ovaries. A group of scientists has achieved a significant milestone in the development of a 3D printed and implantable artificial ovary in mice. In 2017, a research team from Northwestern University achieved a huge milestone when it 3D printed an artificial ovary and implanted it into a sterile mouse. These mouse pups then produced live offspring of their own. This technology will develop by incorporating a clinical trial in pigs, which could someday translate into humans. 3D printed ovaries using hydrogels and IPS cells for woman who have lost their natural ovaries could help woman conceive biological children of their own.